Parietal epithelial cell differentiation to a podocyte fate in the aged mouse kidney
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چکیده
منابع مشابه
Reducing mTOR augments parietal epithelial cell density in a model of acute podocyte depletion and in aged kidneys.
Parietal epithelial cell (PEC) response to glomerular injury may underlie a common pathway driving fibrogenesis following podocyte loss that typifies several glomerular disorders. Although the mammalian target of rapamycin (mTOR) pathway is important in cell homeostasis, little is known of the biological role or impact of reducing mTOR activity on PEC response following podocyte depletion, nor ...
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ژورنال
عنوان ژورنال: Aging
سال: 2020
ISSN: 1945-4589
DOI: 10.18632/aging.103788